Appel Reaction|Mechanism

Appel Reaction Mechanism 

The Appel reaction is a process in organic chemistry that changes an alcohol into an alkyl chloride. This is done by using two chemicals: triphenylphosphine and carbon tetrachloride.

Mechanism Step-1) The Appel reaction starts with the creation of a compound called phosphonium salt.

Step-2) The alcohol loses a proton, forming chloroform, and this creates a compound called alkoxide.

Step-3) The alkoxide ion reacts with the phosphonium salt, creating an intermediate compound.

Step-4) SN2 reaction happens, resulting in a product with 100% inverted configuration (meaning the structure is flipped compared to the original).

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